What does the presence of ovalocytes mean?
Ovalocytes are egg-shaped RBCs commonly associated with vitamin B12 or folate deficiencies or megaloblastic anemias. The more severe the deficiency, the more prevalent the ovalocytes. Ovalocytes are frequently destroyed in the spleen, causing anemia.
What causes ovalocytosis?
Hereditary ovalocytosis is a rare condition passed down through families (inherited). The blood cells are oval-shaped instead of round. It is a form of hereditary elliptocytosis.
What can cause abnormal shaped red blood cells?
Common causes of abnormal red blood cells include:
- Drepanocytes (sickle cells): sickle cell disease.
- Spherocytes (cup shaped): autoimmune disorders, transfusion reactions, diseases of newborns, or snakebites.
- Dacrocytes (teardrop cells): leukemia, megaloblastic anemia, or myelofibrosis.
What is cigar cells?
Cigar cells (also referred to as pencil cells) are red blood cells that are cigar- or pencil-shaped on peripheral blood smear. Cigar cells are commonly associated with hereditary elliptocytosis.
Is it normal to have ovalocytes?
Ovalocytes are red blood cells that have an oval shape rather than the usual round doughnut shape. Ovalocytes are more fragile than normal red blood cells. About 1% of ovalocytes are found in a normal complete blood count.
Can anemia cause ovalocytes?
Iron deficiency anemia, a common type of anemia that is seen when there is insufficient iron in the body, contains elliptocytes (ovalocytes). Megaloblastic anemia caused by a deficiency of either folate or vitamin B-12 contains dacrocytes (teardrop cells), elliptocytes.
When do you see ovalocytes?
Iron deficiency anemia, a common type of anemia that is seen when there is insufficient iron in the body, contains elliptocytes (ovalocytes). Megaloblastic anemia caused by a deficiency of either folate or vitamin B-12 contains dacrocytes (teardrop cells), elliptocytes. [4][5]
What is the difference between ovalocytes and Elliptocytes?
Elliptocytes: Red blood cells are cigar or pencil shaped with parallel sides and an area of pallor. Ovalocytes: Are red blood cells that are oval or egg shaped.
What are Cigar cells in blood smear?
Cigar cell s (also referred to as pencil cells) are red blood cells that are cigar or pencil shaped on Peripheral blood smear. Cigar cells are commonly associated with hereditary elliptocytosis. However, they may also be seen in iron deficiency anemia and other pathological states that decrease red blood cell turnover…
What is the pathophysiology of caudal Cigar cells?
Cigar cells are commonly associated with hereditary elliptocytosis. However, they may also be seen in iron deficiency anemia, sepsis, malaria and other pathological states that decrease red blood cell turnover and or production.
What causes Cigar cells in iron deficiency anemia?
Cigar cells are commonly associated with hereditary elliptocytosis. However, they may also be seen in iron deficiency anemia, sepsis, malaria and other pathological states that decrease red blood cell turnover and or production. In the case of iron deficiency anemia, microcytosis and hypochromia would also be expected.
What is the difference between elliptocytes acanthocytes and erythrocytes?
Definition. Elliptocytes (ovalocytes) range from slightly oval to elongated cigar-shaped forms. Teardrop erythrocytes (dacryocytes) are red cells with one end round and the other end more pointed. Acanthocytes have several (usually 3 to 7) irregularly spaced blunted projections from the margin of the cells.