What is Type 2 dentinogenesis imperfecta?
Overview. Dentinogenesis imperfecta type 2 is a rare and severe form of dentinogenesis imperfecta, a condition that affects tooth development. People affected by the condition may have weak and discolored teeth. These problems can affect both primary (baby) teeth and permanent teeth.
How many types of dentinogenesis imperfecta are there?
There are three types of DI: Type I DI occurs in people who also have osteogenesis imperfecta. This condition is similar in genetic origin but causes brittle bones. Type II DI occurs in people without another hereditary disorder and affects primary more than permanent teeth.
Which type of osteogenesis imperfecta is associated with dentinogenesis imperfecta?
Dentinogenesis imperfecta type I (DGI-I) is also known as opalescent dentin, opalescent teeth with osteogenesis imperfecta, dentinogenesis imperfecta, Shields type I, usually is accompanied by an increase in the incidence of broken long bones of the legs and/or arms because of the increased brittleness of these bones.
What are the 3 types of amelogenesis imperfecta?
The main types are: hypoplastic (type I); hypomaturation (type II); hypocalcified (type III); and hypomaturation/hypoplasia/taurodontism (type IV). AI may be inherited as an X-linked, autosomal dominant, or autosomal recessive genetic trait, depending on the subtype.
Why is dentine dysplasia type II dominant?
Dentin dysplasia type II is caused by mutations of the dentin sialophosphoprotein (DSPP) gene. This mutation is inherited in an autosomal dominant pattern. Dominant genetic disorders occur when only a single copy of a non-working gene is necessary to cause a particular disease.
What is OI type 2?
OI type II is the most severe type of osteogenesis imperfecta. Affected infants often experience life-threatening complications at birth or shortly after. Infants with OI type II have low birth weight, abnormally short arms and legs and blue sclera.
What is Isamelogenesis imperfecta?
Amelogenesis imperfecta is a disorder of tooth development. This condition causes teeth to be unusually small , discolored, pitted or grooved, and prone to rapid wear and breakage.