Does HIV cause lipodystrophy?
Key Points. Lipodystrophy refers to the changes in body fat that can affect some people with HIV. Lipodystrophy can include buildup of body fat, loss of body fat, or both. Lipodystrophy may be due to HIV infection or medicines used to treat HIV, but its actual cause is not understood.
How common is lipodystrophy in HIV?
The exact prevalence of HIV-associated lipodystrophy has been challenging to establish due to differences in case definition, but estimates range from 10% to 80% among all people living with HIV worldwide. [6] The newer HIV medicines are thought to be less likely to cause lipodystrophy than the previously used agents.
What HIV drugs cause lipodystrophy?
Older kinds of drugs to treat HIV like stavudine (d4T, Zerit), zidovudine (AZT, Retrovir), and some of the older protease inhibitors, like indinavir (Crixivan) have been linked to lipodystrophy. The longer you have taken them, the greater your risk seems to be.
How fast does lipodystrophy happen?
Lipodystrophy associated with PIs occurs 2-12 months after starting PI therapy.
Can lipodystrophy be cured?
While there is no cure for lipodystrophy, the conditions that frequently accompany it, like diabetes, can be managed. Patients may also explore cosmetic surgery to address the uneven distribution of fat throughout their body.
How do I know if I have lipodystrophy?
Lipodystrophy is a group of rare disorders characterized by the abnormal utilization and storage of body fat. The most common signs of lipodystrophy are an abnormal distribution of body fat and an insatiable appetite. The condition is classified based on multiple parameters.
Is lipodystrophy curable?
What is lipodystrophy in HIV?
1 Lipodystrophy refers to the changes in body fat that can affect some people with HIV. 2 Lipodystrophy can include buildup of body fat, loss of body fat, or both. 3 Lipodystrophy may be due to HIV infection or medicines used to treat HIV. 4 Lipodystrophy will not be a concern for most people who start HIV treatment now.
What is the cause of lipodystrophy?
Lipodystrophy may be due to HIV infection or medicines used to treat HIV, but its actual cause is not understood. Newer HIV medicines are less likely to cause lipodystrophy than HIV medicines developed in the past.
How accurate is the perception of lipodystrophy in people living with HIV?
People living with HIV on ART have accurate perception of lipodystrophy signs: a cross-sectional study. [BMC Res Notes. 2017] People living with HIV on ART have accurate perception of lipodystrophy signs: a cross-sectional study. Alencastro PR, Barcellos NT, Wolff FH, Ikeda ML, Schuelter-Trevisol F, Brandão AB, Fuchs SC.
What is the prognosis of HIV-associated lipodystrophy?
HIV-associated lipodystrophy is known to cause significant psychological distress and correlates with depression, decreased self-esteem, and social isolation. Patients may become non-compliant due to the fear of the development of lipodystrophy and concern that the presence of lipodystrophy may make the diagnosis of HIV obvious.