What can immunophenotyping diagnose?
Immunophenotyping is used primarily to help diagnose and classify the blood cell cancers, leukemias and lymphomas, and to help guide their treatment.
How is immunophenotyping done?
Immunophenotyping is a test in which the cells in a sample of blood or bone marrow are looked at under a microscope to find out if malignant lymphocytes (cancer) began from the B lymphocytes or the T lymphocytes. The process identifies cells based on the types of antigens or markers on the surface of the cell.
What is Immunophenotypic analysis?
Listen to pronunciation. (IH-myoo-noh-FEE-noh-ty-ping) A process that uses antibodies to identify cells based on the types of antigens or markers on the surface of the cells. This process is used in basic research and to help diagnose diseases, such as specific types of leukemia and lymphoma.
What is immunophenotyping in leukemia?
Immunophenotyping is an essential part of the modern diagnostic workup of acute leukemias and thus for an appropriate treatment of these complex and heterogeneous diseases. It provides a lot of useful information in this setting that transfers directly from laboratory to clinical management of patients.
What blood tests detect lymphoma?
Complete blood count (CBC). This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
What is immunophenotyping in AML?
Immunophenotyping by flow cytometry of bone marrow or peripheral blood samples can be used to help distinguish AML from acute lymphocytic leukemia (ALL) and further classify the subtype of AML.
Which type of lymphoma is curable?
Hodgkin lymphoma is one of the most curable types of cancer. Treatment options include the following: Chemotherapy. Chemotherapy and radiation that directly targets the lymphoma.
Why flow cytometry is done?
Flow cytometry may be used whenever your healthcare provider needs to learn more about the cells inside your body. This type of testing can check the number of immune cells, assess your cell cycle status, identify cancer cells or even analyze your DNA.
What is immunophenotyping?
Immunophenotyping is a test used to identify cells on the basis of the types of markers or antigens present on the cell’s surface, nucleus, or cytoplasm.
What is the immunophenotype of intraepithelial lymphocytes in colon cancer?
The intraepithelial lymphocytes in the adjacent mucosa had identical immunophenotype with tumor cells. The pathological features were reviewed, including histologic type and pertinent immunophenotype of the tumor in the GI specimen.
Why is flow cytometry used in immunophenotyping?
The ability of flow cytometry to determine the presence or absence of cell-surface markers serves as the basis of immunophenotyping.