Is Fluorescence a pH dependence?
Fluorescence decreases with increasing pH and remains stable after pH 6. No emission signals at 530-560 nm at basic pH suggests the absence of deprotonated forms. Among neutral, protonated, and deprotonated forms of 2, the protonated form demonstrated the highest fluorescence (Table 1).
What is the melting point of 4-Methylumbelliferone?
194–195 °C.
Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity. Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.
Is 4-methylumbelliferone polar?
4-Methylumbelliferone is an extremely weak basic (essentially neutral) compound (based on its pKa)….3D Structure for HMDB0059622 (4-Methylumbelliferone)
| Property | Value | Source |
|---|---|---|
| Polar Surface Area | 46.53 Ų | ChemAxon |
| Rotatable Bond Count | 0 | ChemAxon |
| Refractivity | 47.81 m³·mol⁻¹ | ChemAxon |
| Polarizability | 17.42 ų | ChemAxon |
What are the functional groups of 4-methylumbelliferone?
4-methylumbelliferone sulfate is a member of the class of coumarins that is umbelliferone sulfate which carries a methyl group at position 4.
Is fluorescein acidic or basic?
At pH values from 2 to 4, fluorescein exists in its neutral species, and as the pH values become more basic, within the range of 4.3 to 6.4, the monoanionic form is present.
Is fluorescein pH sensitive?
One of the most notorious pH-sensitive probes is fluorescein. In addition to excellent photophysical properties, this fluorophore presents a pH-sensitivity around neutral and physiologic domains.
What is the molar mass of 4-methylumbelliferone?
176.17 g/molHymecromone / Molar mass
Is 4 Methylumbelliferone a base?
4-Methylumbelliferone is an extremely weak basic (essentially neutral) compound (based on its pKa).
What is the molar mass of 4 Methylumbelliferone?