What does NIOSH stand for?
The National Institute for Occupational Safety and Health
NIOSH Regulations The National Institute for Occupational Safety and Health (NIOSH) is responsible for conducting research and making recommendations for the prevention of work-related injury and illness.
What are the three risk groups for hazardous drugs?
DHHS (NIOSH) Publication No. The format for the 2014 list was revised to include three groups of hazardous drugs: (1) Antineoplastic drugs; (2) Non-antineoplastic hazardous drugs; and (3) Drugs with reproductive effects.
Is Flucytosine hazardous?
: No known significant effects or critical hazards.
Which NIOSH drugs are hazardous?
For a more complete list see the NIOSH List of Hazardous Drugs.
- Arsenic trioxide.
- Etoposide.
- Bortezomib.
- Fluorouracil (5-FU)
- Carboplatin.
- Gemcitabine.
- Cisplatin.
- Irinotecan.
What is the highest risk of exposure to hazardous drugs mercy?
The highest risk of exposure occurs during the preparation of hazardous drugs because the drugs are at their most concentrated state at that time. Engineering controls, such as the proper use of BSCs, are the most effective means of reducing employee exposure.
What is the difference between NIOSH approved and NIOSH certified?
NIOSH is aware of falsely used terms such as “NIOSH-approved” and “NIOSH N95” on respirator packaging. Therefore, employers and respirator users should use NIOSH’s Certified Equipment List or the list of NIOSH-approved filtering facepiece respirators to verify respirators are NIOSH approved.
Is flucytosine cytotoxic?
5-fluorocytosine is a prodrug to the cytotoxic compound 5-fluorouracil. Although the exact mode of action is unknown, it has been proposed that flucytosine acts directly on fungal organisms by competitive inhibition of purine and pyrimidine uptake and indirectly by intracellular metabolism to 5-fluorouracil.
Is flucytosine a pro drug?
A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
What is a NIOSH approved mask?
Surgical N95 – A NIOSH-approved N95 respirator that has also been cleared by the Food and Drug Administration (FDA) as a surgical mask. N99 – Filters at least 99% of airborne particles. Not resistant to oil. N100 – Filters at least 99.97% of airborne particles. Not resistant to oil.
What is the most common route of exposure to hazardous drugs?
The most common routes of exposure are skin contact with hazardous drug-contaminated workplace surfaces and inhalation of drug aerosols generated during compounding or administration of hazardous drugs.
What does NIOSH certified mask mean?
the National Institute of Occupational Safety and Health
NIOSH Certification NIOSH stands for the National Institute of Occupational Safety and Health and is a division of the CDC. NIOSH is responsible for N95 mask approval and certifies an N95 as a legitimate particulate respirator.
What does cytotoxic mean?
that kills cells
Listen to pronunciation. (SY-toh-TOK-sik AY-jent) A substance that kills cells, including cancer cells. These agents may stop cancer cells from dividing and growing and may cause tumors to shrink in size.
What kind of drug is flucytosine?
Flucytosine is a medication used in the management and treatment of systemic and severe candida and cryptococcus infections. It is in the antimetabolite, antifungal class of drugs.
What class of drug is flucytosine?
Is NIOSH the same as FDA approved?
The U.S Food and Drug Administration (FDA) approves surgical masks that are to be used by healthcare professionals during surgical procedures. Because NIOSH approved respirators are also used by industrial workers, these are not tested by the FDA, as OSHA requires NIOSH certification.