What is IV IM and SC?
Intravenous (IV), intramuscular (IM), and subcutaneous (SC) are the three most frequently used injection routes in medication administration.
What was the Cantos trial?
The CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcome Study)1 was a randomized, double-blinded, placebo-controlled trial that investigated the use of canakinumab, a monoclonal antibody targeting IL (interleukin)-1β, on high-risk patients with estab- lished atherosclerotic disease who had already survived a …
What is the meaning of IV IM use only?
Route: Intravenous injection (IV) is forcing of a liquid directly into a vein or into a person’s bloodstream while Intramuscular injection (IM) is one made into the substance of a muscle.
Why is Cantos trial important?
The results of the CANTOS trial provide exciting evidence in support of the inflammatory hypothesis of atherosclerosis in humans, and is the first phase III clinical trial to show clinical benefit of a targeted anti-inflammatory therapy.
What was the Cantos trial and what did it show?
The CANTOS trial showed that canakinumab (150 mg) was superior to placebo at preventing adverse cardiac events.
What drug is Z track method?
THE Z-TRACK METHOD of I.M. injection prevents leakage of irritating and discoloring medications (such as iron dextran) into the subcutaneous tissue. It also may be used in elderly patients who have decreased muscle mass.
Why is Z track used?
YOU SHOULD USE the Z-track method for all I.M. injections in adults. By leaving a zigzag path that seals the needle track, this technique prevents drug leakage into the subcutaneous tissue, helps seal the drug in the muscle, and minimizes skin irritation.
How do you use Ilaris?
ILARIS is administered every eight weeks as a single dose via subcutaneous injection. Using aseptic technique, reconstitute each vial of ILARIS by slowly injecting 1 mL of preservative-free Sterile Water for Injection with a 1 mL syringe and an 18 G x 2” needle.
Why is it called Z track?
Pulling the skin and tissue before the injection causes the needle track to take the shape of the letter “Z,” which gives the procedure its name. This zigzag track line is what prevents medication from leaking from the muscle into surrounding tissue. The procedure is usually administered by a nurse or doctor.
What does Z track mean?
(z-trăk′) An injection technique in which the surface (skin and subcutaneous) tissues are pulled and held to one side before insertion of the needle deep into the muscle in the identified site.