Is apoptosis reversible or irreversible?
irreversible
It is currently believed that apoptosis induction may be an irreversible process. Initial results from our laboratory have shown that DNA repair is activated early in p53-induced apoptosis, and that early stages may indeed be reversible.
What is the difference between phosphatidylserine and phosphatidylcholine?
Both are phospholipids, a fatty acid with a hydrophilic head and a hydrophobic double tail. We can convert PC to PS in the body, but not the other way around. PS is more concentrated in the brain, while PC is abundant in cellular membranes and mitochondrial membranes.
What is the main difference between necrosis and apoptosis?
Necrosis is known to be a kind of cell death where the cell dies in an untimely way due to some uncontrolled external factors. Apoptosis is known as a predefined suicide cell where the cell destroys itself maintaining a smooth functioning of the body.
How is apoptosis different than necrosis?
Apoptosis is described as an active, programmed process of autonomous cellular dismantling that avoids eliciting inflammation. Necrosis has been characterized as passive, accidental cell death resulting from environmental perturbations with uncontrolled release of inflammatory cellular contents.
What is the difference between apoptosis and necrolysis?
Necrosis is known to be a kind of cell death where the cell dies in an untimely way due to some uncontrolled external factors. Apoptosis is known as a predefined suicide cell where the cell destroys itself maintaining a smooth functioning of the body. Difference between Apoptosis and Necrosis.
What is apoptosis in biology?
Apoptosis is a programmed cell death. It is a part of normal cell cycle in which old cells die and are replaced by new ones. It is a continuation of cell multiplication process (mitosis). Each cell has a specific life span after which they die and new cells are formed.
What is the difference between apoptosis and oncosis?
The term oncosis has been accepted by many investigators of cell death as a counterpoint to apoptosis (68, 81, 96). Oncosis (from “onkos,” meaning swelling) is defined as a prelethal pathway leading to cell death accompanied by cellular swelling, organelle swelling, blebbing, and increased membrane permeability (Fig. (Fig.2)2) (81).
What happens to apoptotic cells without phagocytosis?
Thus, in the absence of phagocytosis, apoptotic bodies may lose their integrity and proceed to secondary or apoptotic necrosis. Here, the term apoptotic necrosis describes dead cells that have reached this state via the apoptotic program (81).