What is amifostine used for?
Amifostine is used protect the kidneys from harmful effects of the chemotherapy drug cisplatin in patients that receive this medication for the treatment of ovarian cancer. Amifostine is also used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer.
When do you give amifostine?
Amifostine is given by intravenous (into a vein) infusion. The treatment is given before radiation or chemotherapy starts. Patients are given the infusion while lying down and their blood pressure is monitored frequently. Patients may be asked to increase their fluid intake for 24 hours before the infusion.
Is amifostine FDA approved?
Amifostine Trial Represents First FDA Approval of Treatment Interacting With Radiation.
Is amifostine still used?
Based upon these findings, amifostine was approved for use as a radiation protection agent by the FDA for the reduction of xerostomia in pa- tients receiving postoperative head and neck radiation therapy. Till today, amifostine remains the first and only radiation protector that is FDA approved for clinical use.
How long does amikacin stay in the body?
In adults with normal renal function the plasma elimination half-life of amikacin is usually 2-3 hours. 94 – 98% of a single IM or IV dose of amikacin is excreted unchanged by glomerular filtration within 24 hours.
What is the major side effect of amikacin?
Amikacin injection is usually used for serious bacterial infections for which other medicines may not work. However, it may also cause some serious side effects, including damage to your hearing, sense of balance, and kidneys. These side effects may be more likely to occur in elderly patients and newborn infants.
What foods to avoid with mucositis?
Foods to avoid
- Rough-textured or hard foods.
- Tart, acidic or salty foods.
- Spicy foods.
- Really warm foods or drinks.
- Crackers and hard-crust breads.
- Potato chips, pretzels, popcorn and snack chips.
- Citrus fruit and juices.
- Tomato juice.
How long does mucositis take to heal?
Healing usually takes 2 to 4 weeks. Mucositis caused by radiation therapy usually lasts 6 to 8 weeks, depending on how long you have radiation treatment.