What are the side effects of aminophylline?
Side Effects
- Chest pain or discomfort.
- fast, slow, or irregular heartbeat.
- increase in urine volume.
- lightheadedness.
- persistent vomiting.
- pounding or rapid pulse.
- shakiness.
What is the side effect of theophylline?
Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
What is the mechanism of action of xanthines?
The main mechanism of action of xanthine is represented by the inhibition of phosphodiesterase, enzyme that breaks a phosphodiester bond. The pharmacological activity of xanthine is expressed in smooth muscle, heart muscle, central nervous system and kidney.
Can you take theophylline with food?
Take theophylline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Take this medication with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal.
Should you avoid caffeine with theophylline?
Patients taking theophylline should avoid medications containing caffeine when possible. Patients may also need to limit their intake of caffeine-containing beverages or foods (e.g., coffee, green tea, other teas, colas, or chocolate) to avoid caffeine-like side effects.
What is the contraindication of aminophylline?
Aminophylline contraindications include patients with hypersensitivity to theophylline, ethylenediamine, or any component of the drug formulation. Precautions are necessary for patients with concurrent illnesses like: Cardiac disease. Renal impairment.
Is aminophylline a diuretic?
Background: Aminophylline, an established bronchodilator, is also purported to be an effective diuretic and anti-inflammatory agent.
Should theophylline be taken with food?
Does theophylline raise blood sugar?
During the most active phase of glucose counterregulation, the rate of increase of plasma glucose was larger with theophylline (P = . 003 for diabetic patients and P = . 03 for healthy subjects).
Which of the following physiologic effects are produced by xanthines?
Xanthines also produce numerous physiological effects including positive inotropic and chronotropic effects on the heart, decreased airway resistance in the lung, and respiratory stimulation.
What foods should be avoided when taking phenelzine?
Do not eat foods that have dopamine and a high tyramine content (most common in foods that are aged or fermented to increase their flavor), such as cheese (especially strong or aged kinds), caviar, sour cream, liver, canned figs, soy sauce, sauerkraut, fava beans, yeasts, and yogurt.
Can theophylline be taken with food?
Can you drink coffee with theophylline?
Does aminophylline raise blood sugar?
Aminophylline stimulates insulin secretion in patients with type 2 diabetes mellitus. Metabolism.
What is aminophylline toxicity?
Aminophylline is a useful but a potentially toxic drug which may cause severe reactions or even death, due usually to overdosage of or possibly hypersensitivity to the drug. 3. The earliest and most constant symptom of toxicity is restlessness. The next important and almost constant symptom is frequent vomiting.
Can aminophylline cause hypotension?
Both compounds produced a dose-dependent hypotension. Aminophylline frequently caused bradycardia in intact dogs and positive chrono- and inotropic effects in isolated atria.
How is aminophylline metabolized?
Aminophylline is rapidly and completely absorbed by the body and converted to theophylline, up to 40% bound by albumin. The remaining unbound theophylline distributes freely throughout the body except for body fat. The volume of distribution ranges from 0.3 to 0.7 L/kg.
Is theophylline safe in hypertension?
Theophylline may be particularly valuable in patients with a combination of COPD, pulmonary artery hypertension, and right or left heart failure.