What is cutaneous sarcoid?
Because lesions can exhibit many different morphologies, cutaneous sarcoidosis is known as one of the “great imitators” in dermatology. Specific manifestations include papules, plaques, lupus pernio, scar sarcoidosis, and rare morphologies such as alopecia, ulcers, hypopigmented patches, and ichthyosis.
What causes cutaneous sarcoidosis?
Doctors don’t know the exact cause of sarcoidosis. Some people appear to have a genetic predisposition to develop the disease, which may be triggered by bacteria, viruses, dust or chemicals.
Can sarcoidosis become cancerous?
As noted above, sarcoidosis patients have a possibly increased risk of malignancy, either solid or hematological. The increase of the risk of developing solid neoplasia in the course of sarcoidosis seems to be less important than the risk of developing hematological malignancies such as lymphoma (7, 19, 20).
How is cutaneous sarcoidosis diagnosed?
Cutaneous sarcoidosis is generally diagnosed through a skin biopsy. Chest x-rays and lung biopsies may also be performed to confirm a diagnosis of sarcoidosis, because cutaneous sarcoidosis usually accompanies granuloma formation in other organs and most commonly the lungs.
What is cutaneous involvement?
Cutaneous involvement usually represents, or accompanies, Stage IV disease, and carries an ominous prognosis. The problems inherent in the diagnosis of primary cutaneous Hodgkin’s disease are discussed.
How is cutaneous sarcoidosis treated?
Cutaneous sarcoidosis is treated with topical or intralesional (i.e. injected) corticosteroids as the first‐line therapy for localised and mild disease and is generally recommended for disfiguring, cosmetically distressing, and symptomatic disease (Haimovic 2012a).
What is a cutaneous condition?
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands.
Who treats cutaneous sarcoidosis?
Your dermatologist can play a role in diagnosing sarcoidosis by carefully examining your skin for: Lumps, bumps, and other signs. Scars and tattoos (sarcoidosis can develop in one) Lymph nodes near your lumps and bumps.
Is cutaneous the same as skin?
What is a cutaneous disease?
Cutaneous condition refers to any medical condition or disease that affects the organs such as skin, nails, hair and muscles. Cutaneous condition can be a disease in itself or an indication of some other systemic illness.
What is malignancy in patients with sarcoidosis?
Malignancy in patients with sarcoidosis occurs in 3 settings. The first setting relates to patients with hematologic malignancies. It includes the sarcoidosis-lymphoma syndrome, which refers to the development of lymphoma at least 1 to 2 years after the diagnosis of sarcoidosis.
Are You confident of the diagnosis of sarcoidosis?
Are You Confident of the Diagnosis? Sarcoidosis is a multisystem granulomatous disease that can impact almost every organ system of the body. While the majority of patients have pulmonary involvement, a significant subset of patients have cutaneous manifestations.
What are the cutaneous manifestations of sarcoidosis?
Cutaneous manifestations consist of two major categories: lesions specific to sarcoidosis, characterized by granulomatous infiltrates in the skin, and nonspecific lesions resulting from the immunologic response, the classic example being erythema nodosum (EN).
What is sarcoidosis-lymphoma syndrome?
It includes the sarcoidosis-lymphoma syndrome, which refers to the development of lymphoma at least 1 to 2 years after the diagnosis of sarcoidosis. It also includes patients with sarcoidosis who develop other hematologic malignancies.