What type of virus is Flaviviridae?
The Flaviviridae are a family of positive, single-stranded, enveloped RNA viruses. They are found in arthropods, (primarily ticks and mosquitoes), and can occasionally infect humans.
What are the major characteristics of Flaviviridae?
Summary
| Characteristic | Description |
|---|---|
| Typical member | yellow fever virus-17D (X03700), species Yellow fever virus, genus Flavivirus |
| Virion | Enveloped, 40–60 nm virions with a single core protein (except for genus Pegivirus) and 2 or 3 envelope glycoproteins |
| Genome | 9.0–13 kb of positive-sense, non-segmented RNA |
What causes Flaviviridae?
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human populations and cause a spectrum of potentially severe diseases including hepatitis, vascular shock syndrome, encephalitis, acute flaccid paralysis, congenital abnormalities and fetal death.
How many Flavivirus are there?
Flavivirus. This genus consists primarily of >50 species of arthropod-borne viruses, with distinct groups infecting mosquitoes or ticks [1]. Mammals and birds are the usual primary hosts, in which infections range from asymptomatic to severe or fatal haemorrhagic fever or neurological disease.
Is dengue a Flaviviridae?
Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus.
What class of virus is Zika?
Zika virus is a single-stranded RNA virus of the Flaviviridae family, genus Flavivirus.
What are the 7 steps of the life cycle of the flavivirus?
The basic stages of the flavivirus life cycle include attachment to the cell surface, internalization into the host cell, transfer of the viral RNA genome into the cytoplasm, translation of the viral proteins, replication of the genomic RNA, assembly and maturation of the virions, and ultimately the release of progeny …
Is Flaviviridae segmented?
The Flaviviridae are a family of unsegmented positive sense RNA viruses that infect vertebrate and invertebrate species, including the important human pathogens dengue virus, yellow fever virus, and hepatitis C virus.
How do you identify Flavivirus?
Flavivirus-associated human diseases can be reliably confirmed by the detection of viral nucleic acids using conventional reverse transcription (RT)-PCR or real-time RT-qPCR. The molecular diagnosis of flavivirus infection is dependent on the presence of viral nucleic acids in the sampled biological material.
Is Ebola an arbovirus?
The ACAV 1985 catalogue listing includes 12 arenaviruses, four hantaviruses, and Ebola and Marburg, which are not arboviruses but appear in the catalogue because they are viruses likely to be encountered by arbovirus field investigators.
What is the common name for Zika virus?
SUMMARY. Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus Flavivirus and the family Flaviviridae.
What is the difference between segmented and non-segmented viruses?
All of these viruses can be further categorized by the number of genome segments they possess. Those with a single genome segment are referred to as non-segmented, while those with a genome divided into two or more segments are defined according to the scheme by which their genomes are packaged.
Is arbovirus a Flavivirus?
The different types of arbovirus are broken down into specific genera. The three main genera for arboviruses that cause infections in humans are as follows: flavivirus.
Is malaria a Flavivirus?
It includes those diseases caused by alphaviruses (Barmah Forest and Ross River), flaviviruses (dengue, Murray Valley encephalitis, Kunjin, Japanese encephalitis and yellow fever) and malaria.
How many serotypes of dengue virus are there?
The virus responsible for causing dengue, is called dengue virus (DENV). There are four DENV serotypes and it is possible to be infected four times.
Is rabies virus an arbovirus?
Rabies virus is the only medically important member of the rhabdovirus family. It has a single-stranded RNA enclosed within a bullet-shaped capsid surrounded by a lipoprotein (Table 42–5). Because the genome RNA has negative polarity, the virion contains an RNA-dependent RNA polymerase.