What is Trobicin used for?
Trobicin (spectinomycin) For Injectable Suspension is an antibiotic used to treat gonorrhea. Common side effects of Trobicin include nausea, dizziness, soreness at the injection site, hives, insomnia, chills, and fever. The recommended dosage of Trobicin is 2 grams.
What does spectinomycin treat?
Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
How do you administer spectinomycin?
Adults (Men and Women) Inject 5 mL intramuscularly for a 2-gram dose. This is also the recommended dose for patients being treated after failure of previous antibiotic therapy. In geographic areas where antibiotic resistance is known to be prevalent, initial treatment with 4 grams (10 mL) intramuscularly is preferred.
Can spectinomycin treat UTI?
Spectinomycin appears to be of limited value in the treatment of urinary tract infections caused by gram-negative bacilli.
Can spectinomycin cure gonorrhea?
Cervical or anorectal gonococcal infection was eradicated in 54 (98 percent) of 55 women treated with ceftriaxone and 22 (96 percent) of 23 treated with spectinomycin. Cure rates for pharyngeal gonococcal infections were nine of 10 for ceftriaxone and four of eight for spectinomycin (p = 0.18).
Is spectinomycin the same as streptomycin?
Spectinomycin can also be substituted for streptomycin in some cases, and provides more stability, but when increased stability is not required, streptomycin should be used since it is much more cost effective.
What is gonorrhea caused by?
Gonorrhea is a sexually transmitted disease (STD) caused by infection with the Neisseria gonorrhoeae bacterium. N. gonorrhoeae infects the mucous membranes of the reproductive tract, including the cervix, uterus, and fallopian tubes in women, and the urethra in women and men. N.
Is spectinomycin available in the US?
(New York, New York) had discontinued U.S. distribution of spectinomycin (Trobicin®) in November 2005; remaining inventory will expire in May 2006. No other pharmaceutical company manufactures or sells spectinomycin in the United States.
Is streptomycin stronger than penicillin?
It generally is recognized that streptomycin is more effective than penicillin against gram-negative microorganisms and that most strains of gram-positive organisms are more sensitive to penicillin than to streptomycin.
Can you give spectinomycin to dogs?
Spectinomycin has low acute toxicity in mice, rats and dogs when administered by various routes. 6. In numerous repeat dose studies where spectinomycin was administered by injection (i.m, i.v, s.c) the only significant findings were injection site reactions.
Is streptomycin a good antibiotic?
Streptomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by killing the organisms that cause the infection. This drug may also be used to treat other serious infections (such as Mycobacterium avium complex-MAC, tularemia, endocarditis, plague) along with other medications.