What is cross-tolerance?
Cross-tolerance occurs when developing a tolerance for one substance leads to tolerance of another. Most cases of cross-tolerance occur with drugs in the same class that affects similar areas of the body.
What is cross-tolerance pharmacology?
Definition of cross-tolerance : tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action.
What does tolerance mean in drug terms?
Listen to pronunciation. (… TAH-leh-runts) A condition that occurs when the body gets used to a medicine so that either more medicine is needed or different medicine is needed.
What is cross-tolerance in opioids?
Cross-tolerance is the principle underlying methadone substitution in the treatment of heroin addicts. Although methadone produces opioid effects in heroin-addicted subjects, euphoria and side effects are minimized by the tolerance produced by long-term heroin exposure.
What is an example of cross-tolerance?
The most common form of cross-tolerance involves drugs with similar effects because they act on similar parts of the brain. For example, a person who abuses Percocet will develop a cross-tolerance to OxyContin.
What is cross-tolerance quizlet?
Cross Tolerance. -refers to the development of tolerance to one type of drug which results in decreased sensitivity to the effects of another type of drug.
What is an example of cross tolerance?
Sometimes cross-tolerance occurs between two drugs that do not share mechanisms of action or classification. For example, in rats some amphetamine-like stimulants have been shown to exhibit cross-tolerance with caffeine, though this effect was not observed with amphetamine itself.
Which of the following is an example of cross-tolerance?
When tolerance to one drug results in tolerance to another drug What is it referred to as what tolerance quizlet?
When you develop tolerance for a drug you need quizlet?
Developing a tolerance to a drug, means you will need more of the drug to get the same effect.
What is cross tolerance quizlet?
What is meant by tolerance to a drug quizlet?
What is tolerance? A state in which an organism no longer responds to a drug after chronic exposure or a higher dose is required to achieve the same effect.
What are the three types of tolerance to a drug?
Tolerance typically is divided into three functional categories (acute, rapid, and chronic), but determining precisely which molecular underpinning underlies which class of tolerance (or if they are exclusive) can be difficult.
What are the types of drug tolerance?
There are two types of drug tolerance: physiological and behavioral.
What are the three main types of drug tolerance?
Historically, tolerance has been divided into three functional classes: acute, rapid, and chronic (see figure 1) based on how long after exposure to alcohol tolerance develops. Many molecular mechanisms underlie the development of these types of tolerance.
What is cross-tolerance to drugs?
Cross-tolerance occurs when a person develops a physical tolerance to a specific substance, which then translates to tolerance of other drugs. While tolerance may sound like a benefit, when referring to drugs, it means that more of the substance is required to create specific effects.
Cross-tolerance. It often happens between two drugs with similar functions or effects—for example, acting on the same cell receptor or affecting the transmission of certain neurotransmitters. Cross-tolerance has been observed with pharmaceutical drugs such as anti-anxiety agents and illicit substances, and sometimes the two of them together.
What does tolerance mean in pharmacology?
: tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action.
Do μ opioids show cross-tolerance?
Although μ opioids show cross-tolerance, this is often not complete. This is important, particularly when switching drugs in highly tolerant patients. The equianalgesic tables often used to compare doses among opioids were obtained primarily from naïve patients and fall short when used in tolerant patients.